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Hypothetical case: 32 year old male with VSD and Eisenmenger syndrome. Necessary data are given.
Questions:
1) What is the overall Qp/Qs?...1.0
2) Calculate the effective pulmonary blood flow (Qep)….1.17 L/min/m2
3) Calculate the amount of right to left shunt….0.35 L/min/m2
4) Calculate the amount of left to right shunting….0.35 L/min/m2
(From Science and Practice of Pediatric Cardiology, 1990 ed. Page 921)
· O2 content at 100% saturation is 17 g x 1.36 = 23.12 g%.
· Qp:
= (0.95 – 0.60) g% = 120/8.0 (x10 to convert to L/min/m2)
= 120/80 = 1.5 L/min/m2.
· Qs:
Qs = 120/23.1 (0.85-0.50) g% = 120/8.0*10 = 1.5 L/min/m2.
Qp/Qs = 1.0
· Effective PBF (Qep):
Qep – 120/23.1(0.95-0.50) g% = 120/10.4 (x10 to convert to L/min/m2)
= 120/104 = 1.17 L/min/m2.
(Both 1.15 and 1.17 are correct depending upon the calculation step at which you round the numbers. 1.15 is more correct than 1.17)!
· R-L shunt:
(Qp – Qep) = 1.5 – 1.15 = 0.35 L/min/m2
(Pulmonary blood flow includes Qep + R-L shunt via VSD. Therefore, R-L shunt is Qp – Qep)
· L-R shunt:
(Qs – Qep) = 1.5 – 1.15 = 0.35 L/min/m2.
(Systemic blood flow includes Qep + L-R shunt via VSD. Therefore, L-R shunt is Qs – Qep).
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